Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC1L All Species: 20.3
Human Site: S194 Identified Species: 37.22
UniProt: Q13415 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13415 NP_004144.2 861 97350 S194 Q K P V R A K S K S A E S P S
Chimpanzee Pan troglodytes XP_513408 861 97367 S194 Q K P V R A K S K S A E S P S
Rhesus Macaque Macaca mulatta XP_001111614 860 97440 S194 Q K P V G A K S E S A E S P S
Dog Lupus familis XP_532575 858 97161 T194 Q K P V G A K T K A V R S P S
Cat Felis silvestris
Mouse Mus musculus Q9Z1N2 840 95057 L175 P P E V L A A L R E Q E D S P
Rat Rattus norvegicus Q80Z32 848 95741 T188 Q K P L E A K T K S V K S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026457 858 96850 V189 P N S F N S F V P S D I I S S
Frog Xenopus laevis NP_001081806 886 99953 P193 D H N S L P K P L F Y P L E G
Zebra Danio Brachydanio rerio NP_956227 910 101179 L190 R G P Q A R P L P T P D P S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16810 924 103263 T210 R S S R K S L T A H R E S K R
Honey Bee Apis mellifera XP_392056 490 55682
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798977 905 100707 S209 K Q T K K S H S K K P A V S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567440 809 91877 D165 E E D P E I E D C Q I C F K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.7 81.5 N.A. 66 69.8 N.A. N.A. 50.5 52.4 48.6 N.A. 33.4 31.8 N.A. 29.7
Protein Similarity: 100 98.9 97.3 88.8 N.A. 77.9 79.9 N.A. N.A. 66.3 67 63.1 N.A. 52.7 43.5 N.A. 47.1
P-Site Identity: 100 100 86.6 66.6 N.A. 20 66.6 N.A. N.A. 13.3 6.6 6.6 N.A. 13.3 0 N.A. 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 26.6 86.6 N.A. N.A. 20 6.6 26.6 N.A. 40 0 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 27.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 47 8 0 8 8 24 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 8 0 8 0 0 0 0 8 0 0 8 8 8 0 0 % D
% Glu: 8 8 8 0 16 0 8 0 8 8 0 39 0 8 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % F
% Gly: 0 8 0 0 16 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 8 8 8 0 8 % I
% Lys: 8 39 0 8 16 0 47 0 39 8 0 8 0 16 0 % K
% Leu: 0 0 0 8 16 0 8 16 8 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 8 47 8 0 8 8 8 16 0 16 8 8 39 8 % P
% Gln: 39 8 0 8 0 0 0 0 0 8 8 0 0 0 0 % Q
% Arg: 16 0 0 8 16 8 0 0 8 0 8 8 0 0 8 % R
% Ser: 0 8 16 8 0 24 0 31 0 39 0 0 47 31 54 % S
% Thr: 0 0 8 0 0 0 0 24 0 8 0 0 0 0 8 % T
% Val: 0 0 0 39 0 0 0 8 0 0 16 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _